I don't suggest negotiating the continent map.
It gets real costly negotiating everything.
My city can produce 450+ goods a day, and negotiating can drain my resources if I go hog-wild.
I do combat as much as possible.
Gives me tower points, which gives me medals, and medals give me land expansions.
Negotiate only if it's a very hard fight you must get done that day.
Here's my city, right now, at the time of this writing.
I'm using a link to Postimage, so you can see my layout a lot better.
http://s13.postimg.org/5km0hsf7b/Praxis_4_23_2017.jpg
I have 15 goods production buildings.
Most of these buildings are alien to you, but you'll see how I have things arranged.
Unless a building is on an intersection, my buildings are touching only one road.
Keep things tight, no wasted space.
I have some empty space, but I have plans for it in the near future.
Also try to keep your city grid in a square or even rectangle.
Don't branch off with tangents of "arms" coming off your layout.
Put Great Buildings on the edges, so they use a minimum of roads.
Keep in touch if you have any questions.